Anti-RAS (A146P) Mouse Monoclonal Antibody武汉纽斯特生物技术有限公司

性能参数

产品名称: Anti-RAS (A146P) Mouse Monoclonal Antibody
英文名称: Anti-RAS (A146P) Mouse Monoclonal Antibody
抗体货号: 26478
产品规格: 100ul
级    别: 生化级,
产品产地: 美国
品牌商标: NewEastbio
价    格: 4800元
抗原: 小鼠
抗原来源: 
抗体来源: 小鼠
适用物种: 脊椎动物
应用范围: ELISA, WB, IHC
更新时间: 2019/7/9 14:18:00
详细资料: 
浏览人数:434
诚信指数:78点
了解更多:进入公司展台
使用范围:仅限科研使用,不能应用于临床
生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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武汉纽斯特生物技术有限公司
地址:
武汉市东湖新技术开发区光谷生物城B3-3栋2-3楼
邮编:
430074
电话:
027-87561033 手机 18627017297
传真:
027-87561022
联系人:
黄先生
所在区域:
湖北·武汉
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产品详细描述

 

Ras (A146P) [26478]
[100ul]
 

Catalog Number:  26478
Gene Symbol:  H-Ras; K-Ras; N-Ras
Description:   Anti-RAS (A146P) Mouse Monoclonal Antibody
Background:   The A146P mutation of KRas results in an amino acid substitution at position 146, from an alanine to a threonine. KRAS encodes a protein that is a member of the small GTPase superfamily. Ras A146P mutation results in decreased GTPase activity and constitutive signaling. It can be found in many tumors, such as lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Immunogen:   A synthetic peptide from the internal region of Ras which includes the mutation of A146P, human origin.
Applications:   ELISA, IF, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000
IF: 1:50-1:100
IHC: 1:50-1:100
Concentration:   1 mg/ml
Host:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes A146P mutant, but not wild-type RAS of vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
 
Immunofluorescence:  
Immunofluorescence of cells expressing KRas proteins with anti-KRas (A146P) antibody. HEK293T cells were transfected with pCDNA3-GFP-KRas (A146P) plasmid , pCDNA3-GFP-KRas (WT) plasmid, pCDNA3-GFP-KRas (A146V) plasmid or pCDNA3-GFP-KRas (A146T) plasmid, then fixed and stained with anti-KRas (A146P) monoclonal antibody (Cat. #26478).
 

 

Publications:
1.  
    Gene Therapy 21, 888-896 (October 2014)
2.  
    J Clin Pathol. 2015 Aug;68(8):657-60. doi: 10.1136

生物在线声明:以上所展示的信息由企业自行提供,内容的真实性、准确性和合法性由发布企业负责。生物在线对此不承担任何保证责任。

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